Cannabidiol (CBD) is a compound found in cannabis plants, and it can be derived from both hemp and marijuana. Hemp is a plant related to cannabis that contains high concentrations of CBD, but it has almost no THC (below 0.3%). THC is the compound that gives marijuana its psychoactive effects. CBD isolates are those that contain only the CBD molecule, without terpenes, THC or other cannabinoids.
The CBD oil in marijuana can cause you to get high, although the intoxicating effects of these products are less potent considering that CBD counteracts the psychoactive properties of THC. A basic literature search by PUBMED shows numerous articles published in the last 25 years that propose a potential benefit of CBD as a medicine for many purposes. An important aspect to understand when considering the difference between hemp derived CBD and marijuana derived CBD is the resin content of each plant. All physicians should be aware of the impact, not only of THC, but also of CBD on the treatment and prescription of pharmaceuticals to CBD consumers.
CBD isolate is most commonly used in clinical trials to demonstrate that the results are related to CBD rather than to other compounds from any of the plants that may be present. An anecdotal event from a study of a “pure CBD” that was sent for testing was found to have around 75% CBD. Since there is more CBD in cannabis than in hemp, more hemp per dry weight is needed to produce the same amount of isolated CBD. Hemp based CBD oils focus on providing CBD and other cannabinoids or terpenes, while hemp seed oil is not.
If you're looking for the benefits of THC but don't want to get as high as you do with strains with high THC and low CBD content, you can try CBD oil derived from marijuana.